. Hyperhydropectic SYNDROME (ANTIDIABET insipidus, syndrome PARHONA)
Hyperhydropectic syndrome is a rare disease of the hypothalamic-neyrofizarnoy area.At the heart disease is the hyperproduction of vasopressin.More common in women.Parkhomov described in 1933
ETIOLOGY: The causes are usually unknown.All that matters is the mental and physical trauma, infection and lesions in the hypothalamus.A role to play autoimmune and genetic factors.
Pathogenesis: Due to the dysfunction of the hypothalamus, namely the supraoptic, paraventricular nuclei, increased prishodit incretion vasopressin, the main regulator of the osmotic pressure.Vasopressin reduces urine output and contributes to fluid retention.In the progression of the disease involves other endocrine changes regulyatsiivodnogo exchange, in particular, the hyperproduction of aldosterone.
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